CBD oil might help relieve stress, anxiety, seizures, drug withdrawal, and nerve pain. But taking higher doses doesn't always mean they'll have a stronger impact. Also, many studies on CBD have been done on animals, so it's hard to tell if these same effects will apply to people.
Outside of these two disorders, CBD's effectiveness in treating seizures is uncertain. Even with Epidiolex, it's unclear if the anti-seizure effects are from CBD or some other factor.
Many of these interactions are mild and don't demand a change to treatment. Others may require you to substitute the drugs you are taking or to separate doses by several hours.
The study suggests CBD oil may be a good complementary therapy for people whose high blood pressure is affected by stress and anxiety.
If you're thinking of using CBD oil to treat a health condition, talk to your healthcare provider to make sure it's an appropriate option for you.
Possible Side Effects
CBD oil comes in different forms. Isolates contain only CBD, but full-spectrum oils have several compounds from the cannabis plant. This includes proteins, flavonoids, terpenes, and chlorophyll.
Remember that CBD oils are mostly unregulated, so there's no guarantee that a product is safe, effective, or what it claims to be on its packaging.
What’s more, CBD can have serious interactions with certain medications. In evaluating available information on five prescription CBD-based medications, researchers found 139 medications could have a potential drug-drug interaction with CBD  Kocis PT, Vrana KE. Delta-9-Tetrahydrocannabinol and Cannabidiol Drug-Drug Interactions. Medical Cannabis and Cannabinoids. 2020;3:61–73. . People who take certain blood thinners, heart rhythm medications, thyroid medications and seizure medications need to be particularly careful.
(Note: All prices are accurate as of publication and are subject to change.)
Cannabinoids generally have a low bioavailability compared to other substances, according to Jordan Tishler, M.D., a physician specializing in cannabis treatment in Massachusetts. However, “products that contain emulsifiers like egg yolk (brownies) or lecithin (some gummies) do better,” he says.
Like with any substance, you can take more CBD than your body can handle. Studies show doses up to 1,500 milligrams a day have been well-tolerated, but every person is different  Bergamaschi MM, Costa Queiroz RH, Zuardi AW, Crippa JAS. Safety and side effects of cannabidiol, a Cannabis sativa constituent. Current Drug Safety. 2011;6(4):237-49. . Ingesting too much CBD can cause unpleasant side effects, such as dry mouth, nausea, diarrhea, upset stomach, drowsiness, lightheadedness and general disorientation. While rare, liver damage can also occur.
Can You Take Too Much CBD?
CBD oil, on the other hand, makes it easier, to begin with a small dose. But calculating CBD oil dosage can be less straightforward. Oils and tinctures tend to come in a dropper bottle and, typically, only the total liquid volume and CBD contents are listed on the label. For example, the label might simply state there’s 1,500 milligrams of CBD in the 30-milliliter bottle.
FDA-approved Epidiolex administers CBD orally as a liquid to treat seizures associated with Lennox-Gastaut syndrome, Dravet syndrome and tuberous sclerosis complex. The dosage of Epidiolex is determined by taking the patient’s weight in kilograms (kg) into account.
Consumers can choose from a variety of CBD products, from oils to gummies to vapes to capsules. But figuring out the safe and effective CBD dose for an individual is a complex decision.
Penguin CBD Oil
Your CBD product of choice will largely depend on your personal preferences, as well as your budget since prices vary depending on the potency of ingredients and manufacturing processes. Different mediums also offer varying levels of bioavailability—or how much of what you take is actually absorbed into your bloodstream to have an effect. For example, if you ingest 10 milligrams of CBD via 1 milliliter of liquid, your body might absorb about 60% of it, or about 6 milligrams.
If you’re still not sure where to start, mydosage.com offers a questionnaire and CBD calculator to help you based on your specific symptoms and usage goals.