The study also looked at stroke volume (the amount of blood remaining in the heart after a heartbeat). The stroke volume in the men who took CBD was lower than that in the placebo group, meaning the heart was pumping more efficiently.
CBD is the short name for cannabidiol , one of the two chemicals in cannabis with the most health benefits. The other chemical is tetrahydrocannabinol (THC).
CBD oil might help relieve stress, anxiety, seizures, drug withdrawal, and nerve pain. But taking higher doses doesn't always mean they'll have a stronger impact. Also, many studies on CBD have been done on animals, so it's hard to tell if these same effects will apply to people.
Possible Side Effects
Common side effects include:
There are also CBD capsules, CBD gummies, and under-the-tongue CBD sprays.
This cannabis extract may help treat nerve pain, anxiety, and epilepsy
CBD oil might help people with substance use disorder, per a 2015 review in the journal Substance Abuse.
Cytochrome P450 (CYP450) is an enzyme in your body that breaks down certain drugs. But CBD oil can block CYP450 from working the way it normally does. CBD oil can either make some drugs you take have a stronger effect than you need or make them less effective.
Dr. Smita Das, chair of the American Psychiatric Association’s Council on Addiction Psychiatry’s cannabis work group, does not recommend CBD for anxiety, PTSD, sleep or depression. With patients turning to these to unproven products, she is worried that they may delay seeking appropriate mental health care: “I’m dually concerned with how exposure to CBD products can lead somebody into continuing to cannabis products.”
A recent chart review of 72 psychiatric patients treated with CBD found that anxiety improved, but not sleep. “Over all, we did not find that it panned out as a useful treatment for sleep,” said Dr. Scott Shannon, assistant clinical professor of psychiatry at the University of Colorado, Denver and the lead author of the review in The Permanente Journal.
But without clinical trials in humans, psychologists say CBD’s effect on depression is still a hypothesis, and not an evidence-based treatment.
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Is CBD harmful?
Just as hemp seedlings are sprouting up across the United States, so is the marketing. From oils and nasal sprays to lollipops and suppositories, it seems no place is too sacred for CBD. “It’s the monster that has taken over the room,” Dr. Brad Ingram, an associate professor of pediatrics at the University of Mississippi Medical Center, said about all the wild uses for CBD now. He is leading a clinical trial into administering CBD to children and teenagers with drug-resistant epilepsy.
An At-Home Face-Lift
Recently, the F.D.A. sent a warning letter to Curaleaf Inc. about its “unsubstantiated claims” that the plant extract treats a variety of conditions from pet anxiety and depression to cancer and opioid withdrawal. (In a statement, the company said that some of the products in question had been discontinued and that it was working with the F.D.A.)
Does CBD help anxiety and PTSD?
Cannabis containing 0.3 percent or less of THC is hemp. Although last year’s Farm Bill legalized hemp under federal law, it also preserved the Food and Drug Administration’s oversight of products derived from cannabis.
“Our top therapies attempt to break the association between reminders of the trauma and the fear response,” said Mallory Loflin, an assistant adjunct professor at the University of California, San Diego and the study’s principal investigator. “We think that CBD, at least in animal models, can help that process happen a lot faster.” While large clinical trials are underway, psychologists say there isn’t compelling evidence yet as to whether this is a viable treatment.