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cbd and alcohol cravings

Cbd and alcohol cravings

This is a double-blind, placebo-controlled, parallel group study designed to assess the efficacy of fsCBD and bsCBD, compared to a placebo control (PC), to reduce drinking in participants with moderate alcohol use disorder according to the DSM-V. If eligible for the study, subjects will be randomized to receive one of the conditions for 8 weeks.

To minimize risk of COVID transmission, the investigators will utilize Zoom for weekly subject check-ins and our Mobile Pharmacology Lab (MPL) for the collection of blood samples and clinical data for the majority of in-person visits. The initial Week 0 / Baseline visit will take place at the University of Colorado Anschutz Medical Campus. There will be MPL follow-up visits at Weeks 1, 4, and 8. Participants will be contacted by Zoom each remaining week during the 8-week period. A follow up Zoom interview will occur in Week 16 approximately 8 weeks after the end of dosing.

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Overall, the clinical study is expected to take 1-2 years to complete enrollment and data analysis.

The current study will directly test the hypothesis that a moderate dose of CBD leads to a reduction in alcohol consumption, alcohol craving, peripheral markers of inflammation, and anxiety. It is further hypothesized that CBD will lead to increased sleep duration and quality among individuals with AUD who want to quit or reduce their drinking. The study will also determine whether the small amount of THC found in full spectrum hemp-derived CBD products produces any negative effects. The hypotheses are grounded in previous studies suggesting that CBD reduces the reinforcing properties of alcohol and decreases drinking motivation and consumption (Viudez-Martínez, García-Gutiérrez, Fraguas-Sánchez, et al., 2018). Further, CBD has shown clinical promise for tobacco, cannabis, and opioid use disorders (Hurd, 2017; Hurd et al., 2015; Prud’homme et al., 2015), and evidence indicates that these effects may be due to the ability of CBD to reduce cue-induced craving and anxiety (Gonzalez-Cuevas et al., 2018; Hurd et al., 2019). The hypotheses are also grounded in the pre-clinical literature suggesting that CBD may modulate the immune system and have anti-inflammatory effects which also helps to reduce harm associated with alcohol and may have a positive effect on those attempting to quit. Other potential mechanisms that might underlie the effects of CBD include a reduction in the severity of acute withdrawal, a reduction in protracted withdrawal, and the neuroprotective effects of CBD. Given the background literature with respect to CBD and AUDs, a logical next step is for human studies to address these questions.

To better understand the effects of hemp-derived CBD with and without a small amount of THC, the investigators propose a Phase II randomized clinical trial (RCT) to examine the safety, tolerability, and clinical effects of Full Spectrum CBD (fsCBD, contains less than 0.3% THC) vs. Broad Spectrum CBD (bsCBD, does not contain THC), vs. a matching placebo in a population of AUD subjects.

Cbd and alcohol cravings

It’s important to note that while CBD oil may help to take the edge off instantly for many people, its most beneficial potential effects – including inflammation reduction – take place over a period of days or weeks.

CBDPure offers three different versions of CBD oil: 100mg, 300mg, and 600mg. I’m very in tune with my body, meaning that I can usually notice some effect when I take a new supplement. Therefore, I opted to try the 100mg version.

CBDPure uses organic hemp harvested in Denmark, which apparently has some of the highest quality standards for hemp production. The company then uses CO2 extraction to produce its CBD oil here in the U.S. In contrast to more commonly used ethanol or butane, CO2 extraction is a nontoxic and precise method of isolating plant compounds.

The use of CBD for alcohol withdrawal is still a very new phenomenon. There are many promising anecdotal reports about the use of CBD for alcohol withdrawal, but more studies are needed before we can say that CBD has proven benefits for people struggling with alcohol addiction.

Is CBD safe for recovering alcoholics?

The first thing I noticed was that the CBD oil from CBDPure tasted less grassy. It has a light golden color, similar to honey, and tastes earthy without the unpleasant grassiness that I noticed with the brands.

I’m a fan of harm reduction – and I’m not opposed in principle to marijuana use.

If you’ve recently quit drinking, frame early recovery as your own individual journey and enjoy the ride. In the meantime, make sure to optimize your own lifestyle by integrating some healthy lifestyle strategies into your daily routine:

CBD Oil And Alcohol Withdrawal: Conclusion

I believe that CBD may ultimately prove to be very useful in eliminating alcohol dependence for two main reasons:

Since marijuana strains contain varying proportions of these compounds, it can be difficult to determine how much THC or CBD one is consuming when consuming this plant. Generally, indica-dominant strains contain higher levels of CBD, while sativa-dominant strains contain a relatively higher proportion of THC.