Meredith Bull, ND, is a licensed naturopathic doctor with a private practice in Los Angeles, California.
The study authors report that CBD had powerful anxiety-relieving effects in animal research. But the results weren't what you'd expect.
There’s some evidence CBD interacts with seizure medicines like Onfi (clobazam) and boosts their concentration in the blood. More research is needed, though.
This cannabis extract may help treat nerve pain, anxiety, and epilepsy
A 2015 review of studies in the journal Neurotherapeutics suggests that CBD might help treat anxiety disorders.
Instead, CBD influences other receptors, like the opioid receptors that control pain. It also affects glycine receptors. These control serotonin, a brain chemical known as the “feel-good” hormone.
Clinical research has shown that CBD oil can trigger side effects. The severity and type can vary from one person to the next.
The dosages used in research studies vary and there is no consensus on how much should be used for specific conditions. If you do decide to try CBD, it is also important to note that there is no universally agreed upon dose. Research also suggests that people may respond differently to various dosages, so the amount that is right for your needs might vary.
It is also important to remember that CBD products are not regulated by the U.S. Food and Drug Administration (FDA). Some manufacturers make unproven claims about the uses and efficacy of their products. There is also concern about the quality and safety of the products themselves.
If you are targeting specific symptoms of a condition, taking an oil, capsule, or gummy might be a better way to obtain a higher, more concentrated dose.
So what is the maximum amount of CBD you should take? Researchers have found that 600 mg per day appears to be safe, but one study suggested that doses of up to 1,500 mg a day are safe and tolerated well.
This suggests that more research involving more participants and well-designed studies is needed in order to better understand if, how, and why CBD works.